Liverpool boss Rafael Benitez is likely to make changes for his side's second encounter in six days against their city rivals.
Steven Gerrard is set to play after his court appearance and is expected to lead the side at Anfield.
Benitez is likely to recall Javier Mascherano to midfield after the Argentinian was consigned to the bench for Monday's 1-1 home league draw between the sides.
Goalkeeper Diego Cavalieri and full-back Andrea Dossena could be involved. Also in the frame are Ryan Babel, Yossi Benayoun and Lucas while Daniel Agger (calf) and Alvaro Arbeloa (hamstring) will have late fitness tests.
Joseph Yobo could return to Everton's squad after missing the last four matches with a hamstring injury.
However, manager David Moyes is likely to stick with the same side which snatched a late 1-1 draw in the Barclays Premier League encounter at Anfield on Monday.
Provisional Liverpool squad: Reina, Carragher, Hyypia, Skrtel, Aurelio, Dossena, Benayoun, Kuyt, Gerrard, Mascherano, Alonso, Babel, Lucas, Torres, Keane, Riera, Cavalieri, Agger, Aurelio, Plessis, Ngog.
Provisional Everton squad: Howard, Hibbert, Baines, Jagielka, Lescott, Neville, Arteta, Pienaar, Castillo, Cahill, Anichebe, Nash, Van Der Meyde, Yobo, Rodwell, Gosling, Jutkiewicz, Kissock
